One of our major research programs is the development and testing of RNA interference-mediated targeted therapeutics in genetically modified mouse models of glioblastoma which are based on gene mutations found in human tumors. Delivery of therapeutic siRNA is accomplished by the utilization of functionalized Nanoparticles.
In addition, we focus on key basic research questions including functional elucidation of specific gene mutations in the tumorigenic program of glioblastomas and to determine how the cellular context in which the mutations occur influences the outcome of these genetic lesions. Understanding of the biological and genetic determinants of this malignancy will no doubt result in major clinical advances.
Post doctoral positions available. Send your application now to join our team !
